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Life After Whipple Series

The goal of the Life After Whipple Project is to begin to research, collect and disseminate information that may be helpful for pancreatic cancer survivors. This project is for patients who have had, or will have, the Whipple Procedure and are interested in learning how this surgery will affect their lives afterward. Our goal is to help patients learn how to live a successful life, after Whipple.

 

Greg Adams, a pancreatic cancer survivor and team leader of the “Life After Whipple” project, introduces the project providing helpful information for those undergoing or considering the Whipple procedure for pancreatic cancer. Dr. Kwon discusses the anatomy of the pancreas and types of pancreatic operations, focusing on the Whipple procedure and its implications, such as encasement around blood vessels leading to unresectable tumors. The Whipple procedure is a complex six-step operation that involves removing and reconnecting the bile duct, stomach, and pancreas head. Although there are controversies surrounding pylorus preservation, both techniques have comparable long-term effects.

The discussion also highlights complications like Type 3 diabetes, exocrine pancreas insufficiency, delayed gastric emptying, and leakages from pancreatic connections. Medical treatments for weakly squeezing stomachs involve Reglan or Redline. Following the procedure, patients require lifelong acid reduction medication and may face complications like bile reflux and potential hiatal hernias. Foreign patients considering treatment are advised to research and contact international patient services offered by specialized medical centers for the best possible outcome.

HIGHLIGHTS

00:00:00      Introduction of the “Life After Whipple” project and the purpose of this series aiming to disseminate helpful information for pancreatic cancer survivors.

00:05:00      Dr. Kwon explains the anatomy of the pancreas and the types of pancreas operations one may undergo for cancer, focusing on the Whipple procedure and its consequences.

00:10:00      Various stages of pancreatic cancer and whether they are respectable via surgery or not.

00:15:00      The concept of “encasement” in pancreatic cancer, using a CT scan image as an example.

00:20:00     The complex nature of the Whipple procedure, a six-step operation used to remove tumors in the pancreas.

00:25:00     The importance of early detection and symptoms of pancreas cancer and the development in early detection tests on the horizon.

00:30:00     Three components of pancreas reconstruction after the Whipple procedure, focusing on the technical challenges of connecting the pancreas, bile duct, and stomach.

00:35:00    The challenges and techniques used during surgery to secure the pancreatic in place.

00:40:00    Health complications that can arise after undergoing pancreas surgery, specifically Type 3 diabetes and exocrine pancreas insufficiency.

00:45:00    The debate surrounding pylorus preservation during the procedure.

00:50:00    The complications of delayed gastric emptying after the procedure.

00:55:00    Questions answered in regard to surgery in foreign countries.

 

Dr. Kathleen Estrada discusses the functions of the pancreas, focusing on its endocrine role in glucose regulation. The pancreas contains islets of Langerhans, which secrete insulin, glucagon, and somatostatin. Insulin lowers blood sugar levels, while glucagon raises it. Type 3C diabetes, a subtype of diabetes, results from damages to the pancreas and affects exocrine function, leading to insulin and glucagon deficiency, causing blood sugar fluctuations. She also talks about the relationship between insulin production and pancreatectomy locations, with distal pancreatectomy having a higher risk of Type 3C diabetes. The video covers various insulin types and management, the importance of good blood sugar control, the effects of low blood sugar, and recent advancements in technology, such as Continuous Glucose Monitors and insulin pumps. Lastly, Kathleen touches on the experiences and insights of a Whipple procedure survivor regarding blood sugar regulation post-surgery.

 

HIGHLIGHTS

00:00:00     Discussion on the endocrine functions of the pancreas, specifically focusing on glucose regulation.

00:05:00     Type 3C diabetes, a subtype of diabetes that belongs to Type 3 and beyond, which includes conditions affecting the exocrine pancreas.

00:10:00     The relationship between the location of pancreatic resection and the development of Type 3C diabetes.

00:15:00     Different types of insulin used by people with diabetes.

00:20:00    The importance of good blood sugar control for individuals with diabetes.

00:25:00     The insulin pen, a device used for insulin injection, and its side effects & primary functions, specifically low blood sugar.

00:30:00     Recent advancements in diabetes technology, specifically Continuous Glucose Monitors (CGMs).

00:35:00     Advancements in insulin pumps and continuous glucose monitoring systems (CGMs) for managing diabetes.

00:40:00     The Bionic Pancreas, a new device designed to help manage blood sugar levels for people with diabetes.

00:45:00     A survivor discusses the cyclical nature of their blood sugar levels, which alternate between insulin resistance and carbohydrate resistance.

00:50:00     A survivor of pancreatic cancer shares her experiences and offers insights on Type 3C diabetes, which she does not have type 1 or type 2.

 

Dr. Cyrus Piraka, Gastroenterologist, discusses the impact of the Whipple procedure on the gastric system. He highlights that the surgery involves a complete tear-out of the affected organs, including the stomach, duodenum, pancreas, and bile duct, leaving survivors with only essential functions. Dr. Piraka emphasizes the importance of understanding the unique challenges faced by individuals after having a Whipple procedure, as it not only affects cancer patients but also those with benign conditions. The discussion covers the anatomy and physiology of the gastric system, including the stomach, duodenum, pancreas, and bile duct.
Cyrus goes on to discuss the complications associated with the surgery, such as GI tract symptoms, gastroparesis, and digestive enzyme deficiencies. He also touches on the importance of multidisciplinary care and the role of dietitians in managing nutritional complications. He expresses concerns about the insufficient care given to patients after undergoing a Whipple procedure and encourages further research and evidence-based care.
This episode explores the potential connection between pancreatitis and pancreatic cancer, emphasizing the importance of regular evaluation for early detection. While chronic pancreatitis is linked to an increased risk of pancreatic cancer, Dr. Piraka acknowledges the need for further research. He also shares insights on avoiding alcohol consumption after a Whipple procedure, as some doctors advise against it due to its potential impact on the liver and GI system. 

HIGHLIGHTS

00:00:00     The impact of the Whipple procedure on the gastric system

00:05:00     Overview of the digestive process with a focus on the upper GI tract, particularly the stomach and duodenum.

00:10:00     The stomach’s operations & functions and its relation to a tumor environment.

00:15:00     Digestive functions of the stomach, bowel, and how they operate in relation to digestion.

00:20:00    The roles of the pancreas and bile duct in the upper gastrointestinal (GI) tract.

00:25:00     The discussion revolves around the complexities of the digestive system and how it adapts to disease processes.

00:30:00    Long-term complications of the Whipple procedure, which affected nearly half of the patients in a study with a follow-up of at least four years.

00:35:00Challenges in treating gastroparesis, a condition in which the stomach’s nervous system function is disrupted, often after surgery or a cancer diagnosis.

00:40:00    Dietary management and pancreatic insufficiency, common issues post Whipple Procedure.

00:45:00    Two common issues that can arise after bowel surgery, specifically a Whipple procedure.

00:50:00    The importance of dietitians in managing nutritional complications after a Whipple procedure, specifically in regards to gastroparesis and pancreatic insufficiency.

00:55:00    The insufficient care given to patients after undergoing a Whipple procedure, which is used to treat pancreatic cancer.

 

OVERVIEW

Dr. Howard Crawford and Dr. Nina Steele from Henry Ford’s Pancreatic Cancer Center discuss the complexities of the digestive system, focusing on the role of organs like the stomach, salivary glands, and pancreas. They emphasize the importance of understanding the overall system and its functions, both before and after procedures like the Whipple surgery, when addressing digestive issues. Discussion includes the roles of various organs, such as the salivary glands, which produce digestive enzymes, and the stomach, which secretes hormones for nutrient absorption and regulates the digestive process through peristalsis.
The scientists also touch on the intricacies of the nervous system’s role in digestion and how it interacts with different organs. Additionally, they explore the potential for cellular plasticity in the digestive system as a response to the loss of certain functions and Stanford University’s ongoing research in this area. Overall, the conversation revolves around the complexities of the digestive system, the influences of age and surgery on its functions, and the importance of continued research in this field. Ongoing clinical trials focus on preventing pancreatic cancer recurrence are discussed. Trials led by the Mayo Clinic involve patient biopsies and surgeries with tumor sequencing for preventive measures. The success of these immune therapies relies on the elimination of residual disease post-surgery. 

HIGHLIGHTS

00:00:00    Dr. Crawford and Dr. Steele discuss the normal functioning of the digestive system and the potential effects of pancreatic cancer and its treatment on nutrition.

00:05:00    The importance of salivary glands and stomach in the digestive process.

00:10:00Relation between the roles of the stomach in digestion and nutrition.

00:15:00    The complex role of the nervous system, specifically the enteric nervous system, in digestion.

00:20:00    Functions of different regions of the stomach in aiding digestion.

00:25:00    Potential for cellular plasticity in the digestive system, specifically in the case of a total pancreatectomy or after a Whipple procedure.

00:30:00    Roles of various organs in the digestive system, including the pancreas – which is described as having both endocrine and exocrine functions.

00:35:00    The role of the pancreas in regulating glucose levels through the production of insulin and glucagon.

00:40:00    Consequences of losing parts of the digestive tract during surgeries like the Whipple and pancreatectomy.

00:45:00    Personal experiences with digestion and nutrition are shared, specifically regarding the absorption of certain vitamins and fats.

00:50:00    Absorption of nutrients and the role of the microbiome in various parts of the digestive system.

00:55:00    How chemotherapy can affect the endothelial cells in veins and arteries, potentially altering their functionality.

01:00:00    Ongoing clinical trials aimed at preventing pancreatic cancer recurrence.

 

Clinical Health Psychologist Dr. Kelly Martens discusses the impact of fear and anxiety on individuals diagnosed with pancreatic cancer and their coping strategies. Subjects cover fear of recurrence and disease progression, emotional responses, and experiences sharing. Dr. Martin highlights that fear is a normal response, and a study showed surgery patients had lower fear scores initially. However, long-term fear return is prevalent, and coping mechanisms like cognitive behavioral therapy, mindfulness practices, and medication are suggested to manage stressors and distorted thoughts. The video also explores the importance of acceptance, focusing on controllable stressors, and seeking different types of support for emotional, informational, tangible, and social needs. Dr. Martens emphasize the significance of self-advocacy and maintaining a survivorship care plan.
Kelly discusses the experience of living with fear and anxiety, particularly in relation to a serious illness like pancreatic cancer. They advocate for seeking trustworthy health information and prioritizing mental health, encouraging viewers to seek professional help if necessary. Dr. Martens emphasizes the potential benefits of reevaluating priorities and discovering what’s truly important in the face of challenging experiences. Survivors share personal story of surviving pancreatic cancer and the importance of self-value and reprioritization during their journey. Dr. Martens advises viewers to focus on small changes and find meaning in their situations rather than regretting missed opportunities. There is a natural response of fear and anxiety after a cancer diagnosis, and it is important to recognize personal triggers and coping mechanisms.

HIGHLIGHTS

00:00:00    Dr. Kelly Martin from Henry Ford Health discusses the impact of fear and anxiety on individuals diagnosed with pancreatic cancer and their strategies for coping.

00:05:00    Emotional responses of individuals, including themselves, who have undergone surgery for cancer, with a focus on those diagnosed with pancreatic cancer.

00:10:00    A cancer survivor shares her experience of going through surgery and feeling a sense of relief and renewal afterward.

00:15:00    Greg dives into details of his experience surviving cancer and the subsequent challenges of adapting to a new normal.

00:20:00   Connection between fear and anxiety, particularly in relation to a cancer diagnosis, and depression.

00:25:00    The connection between physical & mental symptoms, specifically in the context of fear of recurrence or progression of cancer.

00:30:00    Different types of distorted thoughts that contribute to fear and anxiety, specifically in relation to health concerns. The ultimate goal here is not to eliminate anxiety entirely but to reduce it by shifting one’s perspective.

00:35:00    The importance of acceptance and understanding the power of these thoughts rather than trying to change them.

00:40:00    Using detachment to change the way of thinking and eliminate anxious thinking.

00:45:00    A guest shares her experience with managing anxiety through various methods.

00:50:00    Strategies for coping with stressors, and the importance of advocacy.

00:55:00    The importance of identifying and seeking different types of support, as well as applying self-advocacy to manage fear and anxiety.

01:00:00    Various aspects of living with anxiety and fear, particularly in the context of a serious illness such as pancreatic cancer.

01:05:00    Patty, Greg’s advocate and wife, shares feedback on the importance of self-value and reprioritization during a survivor’s journey.

01:10:00    The normal response of fear and anxiety after a cancer diagnosis, specifically for pancreatic cancer.

 

Dr. Howard Crawford discusses the significant role stress plays in the development and progression of pancreatic cancer. Stress can lead to perineural invasion, a common form of pancreatic cancer metastasis, and the presence of sensory neurons in the pancreas can lead to pain and gut issues experienced by patients. A study by Tim Wong at Columbia University found that isolating mice with precursors to pancreatic cancer and subjecting them to stress accelerated the formation and progression of the cancer. Research also suggests that patients on beta blockers, which reduce stress responses, have a longer survival rate. The discussion also explores personal experiences, early detection strategies, challenges in diagnosis, strategies for reducing stress, and the potential impact of beta-blockers on survival rates.

HIGHLIGHTS

00:00:00    The role stress plays in the development and progression of pancreatic cancer.

00:05:00    A significant finding in the field of cancer research regarding the role of stress in cancer progression.

00:10:00    The interconnected relationship between the nervous system and the pancreas, particularly relevant to pancreatic cancer patients.

00:15:00    Greg shares his personal experience of having ancestors with pancreatic cancer and the possible role of stress as a contributing factor.

00:20:00    The importance of having a support system and keeping an active lifestyle through treatment.

00:25:00    The topic shifts to the potential for early detection of pancreatic cancer through tests on the nervous system.

00:30:00    Generalized discomfort of symptoms related to pancreatic cancer and risk factos to avoid.

00:35:00    The importance of doctors listening to patients’ experiences and considering lesser-known causes of their symptoms to improve early detection and differential diagnosis.

00:40:00    Unique relationship between the pancreas and the nervous system.

00:45:00    Discussion shifts towards strategies for reducing stress in individuals who have had pancreatic cancer.

00:50:00    The potential impact of beta-blockers on the survival rates of pancreatic cancer patients.

00:55:00    The placebo effect and its potential impact on reducing stress.

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End-of-Life Care & Grief Resources

Guidance on hospice, palliative care, and grieving with support.

Overview: Preparing for the later stages of the journey.

  • Understanding palliative vs. hospice care
  • Having difficult conversations with your loved one
  • Planning for legal and financial decisions
  • Coping with grief and finding support after loss

End-of-Life Care & Grief Resources

The later stages of pancreatic cancer often bring difficult decisions about care, comfort, and quality of life. For caregivers, family members, and friends, these moments are emotionally overwhelming. At Sky Foundation, we understand this deeply—our board, committees, and communities are filled with survivors and families who have faced these realities. This resource is here to help you navigate end-of-life care and grief with compassion and clarity.

Understanding Palliative vs. Hospice Care

Palliative care can begin at any stage of illness and focuses on symptom relief, emotional support, and quality of life alongside treatment.

Hospice care is typically recommended when life expectancy is six months or less. It emphasizes comfort, dignity, and support for both the patient and the family.

As a caregiver, ask your loved one’s medical team:

  • What symptoms can palliative care help with now?
  • When is hospice the right choice?
  • How can hospice support caregivers and families?

 

Preparing for Difficult Conversations

Facing the reality of end-of-life care requires open, compassionate communication.

  • Talk about wishes early: Ask about preferred settings for care (home, hospital, or hospice facility).
  • Document decisions: Use advance directives, living wills, or healthcare proxies.
  • Involve the whole family: Hold family meetings to share updates and avoid miscommunication.
  • Acknowledge emotions: Fear, sadness, or disagreement is natural—listening is as important as planning.

Supporting Caregivers & Families During End-of-Life

The emotional weight on caregivers during this stage is immense. Practical steps can help:

  • Accept help with meals, errands, or caregiving shifts.
  • Ask hospice teams about respite care options.
  • Take time for breaks, even short walks or naps.
  • Seek counseling or caregiver support groups to process grief in real time.

 

Grief Support After Loss

Grief is not linear—it unfolds differently for everyone. Some may feel deep sadness, while others feel numb or even relieved that their loved one is no longer suffering. All reactions are valid.

  • Give yourself permission to grieve: Avoid self-criticism for how you “should” feel.
  • Seek support groups: Talking with others who’ve experienced loss can reduce isolation.
  • Honor your loved one’s memory: Journaling, creating a photo book, or joining a memorial event can bring healing.
  • Support children and teens: Encourage open expression and age-appropriate explanations.

 

Key Takeaway

End-of-life care and grief are among the most difficult parts of the pancreatic cancer journey. By understanding the role of palliative and hospice care, having honest conversations, and seeking grief support, caregivers and families can honor their loved one’s wishes while protecting their own well-being. Sky Foundation provides survivor-led communities, caregiver support, and Legacy Giving opportunities to ensure your loved one’s story continues to inspire hope and change.

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Next Steps After Pancreatic Cancer Diagnosis

A pancreatic cancer diagnosis raises urgent questions: What should I do first? Where do I go for care? What information do I need?
The following steps are widely recommended by leading cancer centers and medical guidelines.

1. Confirm the Diagnosis and Stage

Accurate diagnosis is essential before making treatment decisions. Tests may include:

  • Imaging scans – CT, MRI, or PET to identify tumor location and spread.
  • Endoscopic ultrasound (EUS) – allows close imaging and tissue biopsy.
  • Biopsy – confirms cancer type under a microscope.
  • Blood tests – including CA 19-9, a tumor marker sometimes elevated in pancreatic cancer.

These results help determine whether the cancer is localized, borderline respectable, locally advanced, or metastatic.

📖 Resource: American Cancer Society – Pancreatic Cancer Diagnosis

2. Seek a Second Opinion

Pancreatic cancer is complex and outcomes improve when treatment decisions are made by multidisciplinary teams at high-volume centers. Even if you feel confident in your current provider, a second opinion can confirm staging, expand your treatment options, and ensure surgical expertise is available.

Sky Foundation partners with Henry Ford Health and nationally recognized pancreatic surgeons to provide these expert evaluations. Please contact us for a connection to the team of doctors we suggest. 

3. Undergo Genetic and Biomarker Testing

Both germline (inherited) and somatic (tumor-specific) genetic testing are now standard of care for all pancreatic cancer patients. These tests can:

  • Identify inherited syndromes that may affect family members.
  • Reveal mutations (such as BRCA1/2, PALB2, MSI-H, KRAS, or NTRK) that guide targeted therapies or trial eligibility.
  • Inform risk for other cancers.

📖 Resource: National Cancer Institute – Pancreatic Cancer Genetics

4. Understand Treatment Pathways

Treatment depends on the stage and overall health of the patient. Standard approaches include:

  • Surgery – the only potentially curative option, performed if the tumor can be safely removed. The Whipple procedure (pancreaticoduodenectomy) is the most common.
  • Chemotherapy – drugs such as FOLFIRINOX or gemcitabine-based regimens, given before (neoadjuvant) or after (adjuvant) surgery, or as primary treatment for advanced disease.
  • Radiation therapy – may be used in selected cases to shrink tumors or relieve symptoms.
  • Palliative care – managing symptoms, nutrition, and quality of life from the start of treatment.

📖 Resource: NCCN Guidelines for Patients – Pancreatic Cancer

5. Explore Clinical Trials Early

Clinical trials test new drugs, combinations, and therapies. Enrolling early provides access to promising treatments that may improve outcomes beyond standard care.

Sky Foundation can help identify trials in Michigan and nationally.  Karmanos Cancer Institute (KCI) is a National Cancer Institute (NCI) Designated Comprehensive Cancer Center and has been since 1978. We are one of only 57 centers located in the United States. KCI is the only cancer hospital in the state of Michigan and our NCI designation ensures that we demonstrate scientific excellence as well as expertise in clinical, laboratory,  behavioral and population-based research. We offer our patients cancer treatment and clinical trials not available at other hospitals, as well as welcome patients coming in for consultation for a second opinion.

Karmanos Cancer Institute – https://www.karmanos.org/karmanos/clinical-trials-at-karmanos-cancer-institute

📖 Resource: ClinicalTrials.gov – Pancreatic Cancer Studies

6. Build Your Care Team

A strong care team typically includes:

  • Surgical oncologist – for surgical options.
  • Medical oncologist – for chemotherapy and systemic therapy.
  • Radiation oncologist – for targeted radiation when indicated.
  • Gastroenterologist – for digestive issues and stent placement.
  • Genetic counselor – for inherited cancer risk assessment.
  • Nutritionist and palliative care specialists – for symptom and diet management.

Multidisciplinary coordination improves survival and quality of life.

📖 Resource: Mayo Clinic – Pancreatic Cancer Treatment Team

7. Prepare for Appointments

Bring a trusted family member or caregiver to appointments and keep written questions. Helpful questions include:

  • What type and stage of pancreatic cancer do I have?
  • Is my cancer potentially operable?
  • What genetic or biomarker tests are recommended?
  • What are the treatment options in my situation?
  • Am I eligible for any clinical trials?
  • What side effects should I expect?

📖 Resource: American Cancer Society – Questions to Ask Your Doctor
📖 Resource:Sky Foundation Inc – Questions for Yourself & Medical Team

8. Consider Supportive Resources

Newly diagnosed patients and caregivers benefit from:

  • Patient navigation programs for clinical trial matching and insurance questions.
  • Survivor and caregiver support groups to reduce isolation.
  • Financial and legal counseling for managing treatment costs.

📖 Resource: CancerCare – Pancreatic Cancer Support

Here are some of the organizations we work closely with and collaborate on patient resources:

Key Takeaway

Your first steps should include confirming the diagnosis, seeking expert opinions, and undergoing genetic testing. Building a multidisciplinary care team and considering clinical trials early can expand treatment options and improve outcomes.

NEXT ARTICLE: Treatment Options

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Episode #101: The Whipple Procedure

Greg Adams, a pancreatic cancer survivor and team leader of the “Life After Whipple” project, introduces the project providing helpful information for those undergoing or considering the Whipple procedure for pancreatic cancer. Dr. Kwon discusses the anatomy of the pancreas and types of pancreatic operations, focusing on the Whipple procedure and its implications, such as encasement around blood vessels leading to unresectable tumors. The Whipple procedure is a complex six-step operation that involves removing and reconnecting the bile duct, stomach, and pancreas head. Although there are controversies surrounding pylorus preservation, both techniques have comparable long-term effects.

The discussion also highlights complications like Type 3 diabetes, exocrine pancreas insufficiency, delayed gastric emptying, and leakages from pancreatic connections. Medical treatments for weakly squeezing stomachs involve Reglan or Redline. Following the procedure, patients require lifelong acid reduction medication and may face complications like bile reflux and potential hiatal hernias. Foreign patients considering treatment are advised to research and contact international patient services offered by specialized medical centers for the best possible outcome.

HIGHLIGHTS

00:00:00      Introduction of the “Life After Whipple” project and the purpose of this series aiming to disseminate helpful information for pancreatic cancer survivors.

00:05:00      Dr. Kwon explains the anatomy of the pancreas and the types of pancreas operations one may undergo for cancer, focusing on the Whipple procedure and its consequences.

00:10:00      Various stages of pancreatic cancer and whether they are respectable via surgery or not.

00:15:00      The concept of “encasement” in pancreatic cancer, using a CT scan image as an example.

00:20:00     The complex nature of the Whipple procedure, a six-step operation used to remove tumors in the pancreas.

00:25:00     The importance of early detection and symptoms of pancreas cancer and the development in early detection tests on the horizon.

00:30:00     Three components of pancreas reconstruction after the Whipple procedure, focusing on the technical challenges of connecting the pancreas, bile duct, and stomach.

00:35:00    The challenges and techniques used during surgery to secure the pancreatic in place.

00:40:00    Health complications that can arise after undergoing pancreas surgery, specifically Type 3 diabetes and exocrine pancreas insufficiency.

00:45:00    The debate surrounding pylorus preservation during the procedure.

00:50:00    The complications of delayed gastric emptying after the procedure.

00:55:00    Questions answered in regard to surgery in foreign countries.

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The Importance of Self Advocacy

No one expects to be told they have pancreatic cancer in the emergency room, with less than a 1% chance of survival, but that’s exactly what happened to Greg Adams. Determined to find another path, he sought six second opinions, ultimately raising his chances to 2%, and in his words “doubling my odds!” That gave him the drive to keep fighting.

Today, Greg is a seven-year survivor who spends much of his time helping others navigate diagnosis and recovery. His Life After Whipple program, featured on Sky Foundation’s YouTube channel, has become a lifeline for patients searching for answers, clarity, and hope at a time when support can feel scarce. He also helped launch our Sky Support Circle, a team of “Sky Advocates” who stand with newly diagnosed individuals and their families during the most uncertain moments of their lives.

At Sky Foundation, our mission is raising awareness and funding innovative research for early detection and treatment of pancreatic cancer. We encourage our community to learn the symptoms, understand personal risk factors, get genetic testing, and advise newly diagnosed patients to explore clinical trials. We provide vital information, trusted resources, and a compassionate community for patients, caregivers, and survivors.

Greg’s courage and advocacy for himself reflects a truth at the heart of Sky Foundation: patients deserve more than a prognosis—they deserve possibilities.

Your gift today ensures Sky can continue to offer guidance, education, and connection to those facing one of the most challenging diagnoses imaginable.

Thank you for being a vital partner in this journey.

 

Read about Greg’s full story here. 

 

Make a year end gift here:

 

 

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Sky Support Circle

Continuing the Legacy of Compassion

The Sky Support Circle was created in the spirit of our founder, Sheila Sky Kasselman, who built Sky Foundation on one simple but powerful belief — that no one facing pancreatic cancer should ever feel alone.

When patients or families reached out, Sheila personally answered their calls. She shared honest, heartfelt advice drawn from her own experience as a survivor and advocate. She offered direction on the patient side of things — how to manage chemo treatments, what to expect during recovery, and how to find emotional stability through an incredibly difficult journey.

Sheila also connected patients directly to her network of trusted specialists, providing personal referrals to Michigan’s leading hospital systems and oncologists — helping families find the right medical team quickly when time mattered most. Her dedication, compassion, and hands-on support inspired this program that continues her work today.

Meet Our Sky Advocates

Our Sky Advocates are the heart of the Support Circle — volunteers and survivors who carry on Sheila’s mission by offering:

  • One-on-one guidance and emotional support

  • Personal connections to hospitals, programs, and specialists

  • Insight from lived experiences with pancreatic cancer

Each advocate is trained to listen, guide, and connect — helping patients, survivors, and caregivers find the right resources, second opinions, and emotional grounding as they navigate this journey.

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Sky Advocate Leader

Greg Adams

Pancreataic Cancer Survivor

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🩺 Patient & Caregiver Resources

We’ve created an easy-to-navigate library of tools and links designed to support every step of your journey:

Whether you’re newly diagnosed, supporting a loved one, or looking for specific programs, this section includes everything from treatment FAQs to local and national support services.

Clinical Trials Navigation

Sky Foundation is proud to collaborate with TriCan Health, a platform that simplifies finding and enrolling in pancreatic cancer clinical trials.

Our upcoming “How to Use TriCan” video will walk you through step-by-step instructions on how to search, filter, and connect with ongoing trials near you — empowering you to explore every treatment option available.

Visit TriCan’s Website

🌅 Life After Whipple Series

For many survivors, life after the Whipple surgery looks very different — physically, emotionally, and nutritionally.

Our Life After Whipple Series brings together experts, surgeons, and survivors to discuss practical guidance for post-surgery life, including digestive changes, nutrition tips, emotional recovery, and rebuilding quality of life.

Watch the Life After Whipple Series

🛣️ The Road of Support

No one walks this road alone.
Our Road of Support pamphlet features trusted nonprofit partners that provide financial assistance, emotional care, and community programs for patients and caregivers.

View the Road of Support

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Pancreatic Cancer Resources for Patients & Caregivers | Sky Foundation

Pancreatic cancer impacts not only the patient but also caregivers, family members, and loved ones. Accessing trusted resources can help with treatment planning, financial challenges, and emotional support.

Patient Navigation Services

Patient navigators are professionals who help guide patients through the healthcare system. They coordinate care, assist with scheduling, explain treatment options, and provide referrals for clinical trials. Many major cancer centers, including Henry Ford Health and the National Cancer Institute (NCI)-designated centers, offer navigation programs.

 

Financial and Legal Assistance

The cost of treatment can be a major concern. Several organizations provide financial and case management support:

Support for Caregivers

Caregivers play a vital role in managing appointments, medications, and emotional support. Dedicated caregiver programs can reduce burnout and improve patient outcomes.

Helpful tools include:

  • Caregiver workbooks for organizing medical information.
  • Respite care programs to provide temporary relief.
  • Counseling services for caregiver stress and grief support.

 

Educational Materials

High-quality educational guides help patients and caregivers make informed choices. Trusted options include:

  • Life After Whipple: The premier video series that documents everything you need to know about living post-Whipple surgery.
  • Lustgarten Foundation – Navigating Pancreatic Cancer Handbook: Comprehensive patient and caregiver guide.
  • National Comprehensive Cancer Network (NCCN) – Patient Guidelines: Evidence-based, plain-language explanations of diagnosis and treatment. 
  • American Cancer Society – Pancreatic Cancer Resources: Detailed information on symptoms, treatment, and coping strategies

Community & Peer Support

Engaging with peers and support groups helps reduce isolation and provides practical advice from those with lived experience. Options include:

Nutrition and Symptom Management

Since the pancreas is critical for digestion, patients often require dietary modifications. Resources can help with:

  • Pancreatic enzyme replacement therapy (PERT).
  • Medical nutrition counseling to maintain weight and strength.
  • Palliative care specialists for pain, fatigue, and symptom relief.
  • Life After Whipple Dietary Guidance – Digestion & Nutrition Episode

📖 Resource: Johns Hopkins Medicine – Nutrition and Pancreatic Cancer
📖 Resource: National Cancer Institute – Palliative Care
📖 Resource: Life After Whipple – Digestion & Nutrition

Key Takeaway

Patients and caregivers do not have to face pancreatic cancer alone. A wide range of resources—from financial assistance and patient navigation to peer support and nutrition guidance—are available to reduce stress and improve quality of life during treatment.

 

NEXT ARTICLE: Glossary & FAQ

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Questions to ask Yourself and your Medical Team

Please join Sky Foundation’s Support Circle for one-on-one support and personal referrals to additional resources.

 

WHAT IS PANCREATIC CANCER?

  • What type of pancreatic cancer do I have? Pancreatic Adenocarcinoma vs. Neuroendocrine Cancer
  • Have you treated pancreatic cancer before? Is it your specialty?
  • What has the general outcome of those patients been?
  • Do each patient have a full medical care team? Do you assemble it or do I?

WHAT ARE MY TREATMENT OPTIONS?

  • What treatments are recommended?
  • If this is a surgeon, how many surgeries have you performed on pancreatic cancer patients? Is surgery a possibility to treat this cancer?
  • What is Whipple Surgery? 
  • What can I expect for the recovery of Whipple surgery? 
  • Are there other treatment options available that you do not provide? (i.e., protocol treatments, herbal therapy, touch therapy, other alternative therapies, clinical trials)
  • What are the risks and benefits of each treatment?
  • What are the medications being prescribed? What are they for? What are their side effects?
  • How should I expect to feel during the treatment(s)?

WHO IS ON YOUR TEAM AND ARE YOU PREPARED FOR LIFE CHANGES?

  • What other professionals should I have as part of my medical team?
  • Do you recommend a nutritionist?
  • Do you recommend a psychologist and therapist?
  • Should I do genetic testing? Is this hereditary? 
  • How will pancreatic cancer affect my quality of life?
  • How will pancreatic cancer affect my ability to work?
  • What are possible physical limitations?
  • Will my current lifestyle be changed?

ARE YOU A PRIORITY FOR YOUR MEDICAL TEAM?

  • Does my doctor appear interested in me personally and my diagnosis?
  • Do I feel that my doctor cares about my medical outcome?
  • Do you have psychological and emotional support? Family and professional support are both important.
  • Are you comfortable with your medical team?
  • Have you had an additional consultation with another doctor? Should I get a second or a third opinion?
  • Most importantly, take an additional person to your medical appointments and record doctor/patient conversation so you can go back and review the provided information.

ADDITIONAL EMOTIONAL AND FINANCIAL SUPPORT RESOURCES: Sky’s Road Map For Patients, Families and Friends:

Click here: Road Map for Patients

SUPPORT GROUPS

  • It always difficult when you or someone close to you is diagnosed with cancer. It is critical to have support for the patient, the family and friends during this difficult time. Here are a two resources in the metropolitan Detroit area that offer various support groups to help you through your journey.
read more

David S. Kwon, MD

David S. Kwon, MD, FACS, FSSO

Board-Certified Surgeon | Fellowship-Trained Surgical Oncologist | Clinical Director, Henry Ford Pancreatic Cancer Center

Overview

Dr. David S. Kwon, MD, FACS, FSSO is a board-certified general surgeon and fellowship-trained surgical oncologist at Henry Ford Health. He serves as Physician in Charge of the Brigitte Harris Cancer Pavilion and Clinical Director of the Henry Ford Pancreatic Cancer Center, leading multidisciplinary teams focused on precision medicine and complex cancer care (Henry Ford Health).

Leadership & Roles

  • Physician in Charge – Brigitte Harris Cancer Pavilion, overseeing multidisciplinary oncology programs and precision-based patient care (CBS Detroit).
  • Clinical Director – Henry Ford Pancreatic Cancer Center, driving innovation in early detection and treatment (PR Newswire).
  • Former Medical Director – Center for Cancer Surgery, Henry Ford Health (Crain’s Detroit).
  • Faculty Member – Wayne State University School of Medicine.

Education & Training

  • B.S., Biological Sciences – Columbia University
  • M.D. – University of California, San Diego
  • Residency – General Surgery, Henry Ford Hospital (multiple research & clinical awards)
  • Fellowship – Surgical Oncology, The University of Texas M.D. Anderson Cancer Center

Clinical Expertise

  • Pancreatic, gastric, and rare cancers
  • Complex foregut and hepatopancreatobiliary surgery
  • HIPEC and cytoreductive surgery for peritoneal surface malignancies
  • Precision medicine and multidisciplinary cancer management

Research & Innovation

Dr. Kwon’s research focuses on pancreatic cancer detection, disparities, and advanced local therapies. His team contributes to pioneering work in molecular and spatial phenotyping, immune checkpoint targets such as TIGIT, and artificial intelligence for imaging-based cancer detection (PubMed).

  • Borderline/Locally Advanced Pancreatic Adenocarcinoma: Margin accentuation with intraoperative irreversible electroporation (Surgery, 2014).
  • Neoadjuvant vs. Adjuvant Therapy Studies: Comparative outcomes in resectable PDAC (Int J Radiat Oncol Biol Phys, 2018).
  • Single-Cell & Spatial Phenotyping: Racial disparity studies in PDAC (AACR Abstracts, 2024).
  • AI-Driven Cancer Detection: Co-author on deep learning for pancreatic tumor diagnosis (npj Digital Medicine, 2024).

Patient Education & Community Engagement

Dr. Kwon regularly contributes to Henry Ford Health’s educational resources and public outreach. He’s been featured in patient programs and community events like “Life After Whipple,” offering insight into surgical recovery and survivorship (Henry Ford Health Blog).

Honors, Memberships & Service

  • Fellow, American College of Surgeons (FACS)
  • Fellow, Society of Surgical Oncology (FSSO)
  • Active in national surgical oncology mentorship and leadership initiatives
  • Featured in Crain’s Detroit People on the Move for leadership in cancer surgery and multidisciplinary care

Career Timeline

  • Columbia University – B.S., Biological Sciences
  • UC San Diego – M.D.
  • Henry Ford Hospital – General Surgery Residency
  • MD Anderson Cancer Center – Surgical Oncology Fellowship
  • 2011: Returns to Henry Ford Health as Surgical Oncologist
  • 2015: Appointed Division Head, Surgical Oncology
  • 2016: Named Medical Director, Center for Cancer Surgery
  • 2020: Named Clinical Director, Henry Ford Pancreatic Cancer Center
  • 2021–Present: Physician in Charge, Brigitte Harris Cancer Pavilion

Conditions & Programs

  • Pancreatic and gastric cancers
  • Rare and peritoneal malignancies (including mesothelioma)
  • HIPEC and cytoreductive surgery
  • Precision-medicine and multidisciplinary clinic coordination

Sources

  • Henry Ford Health – Brigitte Harris Cancer Pavilion & HIPEC Program
  • CBS Detroit – Pavilion Grand Opening
  • PR Newswire – HFPCC Philanthropy Announcements
  • Crain’s Detroit – Leadership Recognition
  • PubMed, AACR, npj Digital Medicine – Research Publications
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Recently Diagnosed with Pancreatic Cancer | Sky Foundation Guide – TEST

Next Steps After a Pancreatic Cancer Diagnosis

Being diagnosed with pancreatic cancer can feel overwhelming. This page provides accurate information, structured guidance, and trusted resources to help you understand your diagnosis and take your next steps with confidence.

Table of Contents

1) Start Here
Understanding Your Diagnosis
What it is, types, and staging basics.

 

 

2) Do This Next
Next Steps After Diagnosis
Your step-by-step checklist.

 

 

3) Options
Treatment Options
Surgery, chemo, radiation, more.

 

 

4) Consider Early
Clinical Trials Access
Match your case to trials.

 

 

5) Get Help
Resources for Patients & Caregivers
Financial, caregiver, navigation.

 

 

6) Quick Definitions
Glossary & FAQ
Common terms & questions.

 

Understanding Your Diagnosis

Pancreatic cancer begins in the pancreas, an organ that helps regulate blood sugar and produces enzymes for digestion.
The most common type is pancreatic ductal adenocarcinoma (PDAC), which arises in the ducts of the pancreas.
Less common types include neuroendocrine tumors.

Staging (localized, borderline resectable, locally advanced, or metastatic) is determined through imaging (CT, MRI, EUS) and biopsy.

Next Steps After Diagnosis

Use this checklist to stay organized and move forward with clarity. You don’t have to do everything at once—start with Step 1 and build from there.

Step 1
Confirm Your Diagnosis and Stage
Use imaging, biopsy, and bloodwork (including CA 19-9) to confirm the diagnosis and determine the stage of pancreatic cancer.
Step 2
Seek a Second Opinion
Outcomes often improve when care is coordinated through high-volume cancer centers. Sky Foundation partners closely with
Henry Ford Health,
Karmanos Cancer Institute, and the
University of Michigan Rogel Cancer Center—and we can help connect you directly to any of these hospital systems upon request.

Step 3
Understand Your Treatment Pathways
Common options include surgery, chemotherapy, radiation, clinical trials, and palliative care. Understanding each pathway helps you and your care team make informed decisions tailored to your needs.
Step 4
Explore Clinical Trials Early
Access to new and emerging therapies can improve survival and quality of life. We recommend
TriCan Health,
which can match your specific case details to active clinical trials that may be the best fit for you.
Step 5
Build a Multidisciplinary Care Team
Assemble a team that includes experienced surgeons, oncologists, gastroenterologists, and nutritionists. If you’re a candidate for the
Whipple procedure, research your surgeon carefully—experience matters. Look for someone who has performed hundreds, ideally thousands of successful Whipple surgeries.
Step 6
Prepare for Appointments
Bring a trusted caregiver and a written list of questions to each visit. Staying organized ensures you get the answers and support you need.
Refer to our
questions for yourself and your medical team page.

Treatment Options

🩺 Surgery
Whipple procedure, distal pancreatectomy, or total pancreatectomy (curative intent).
💉 Chemotherapy
FOLFIRINOX, gemcitabine + nab-paclitaxel, or gemcitabine alone.
☢️ Radiation Therapy
For borderline resectable or locally advanced disease, or symptom relief.
🧬 Targeted Therapy & Immunotherapy
PARP inhibitors for BRCA1/2 mutations; pembrolizumab for MSI-H tumors.
🧪 Clinical Trials
Options may be available at multiple stages of care—not just as a last resort.
🤝 Palliative Care
Pain management, nutrition counseling, enzyme replacement, and emotional support.

Clinical Trials Access

Clinical trials test new therapies, including targeted drugs and immunotherapies. Patients often benefit from enrolling early.
Clinical trials are often looked at when patients “have no other options.” But in the words of pancreatic cancer survivor, Kay Kays:
“Clinical Trials should be the appetizer, not the dessert.”

Resources for Patients & Caregivers

Support & Emotional Well-Being

🧠 Counseling & Mental Health
Emotional health is an important part of your care. Oncology social workers, psychologists, and cancer support groups can help manage anxiety, depression, and the emotional challenges that come with a diagnosis.
🫶 Peer Support Communities
At Sky Foundation, our community includes many individuals who have personally experienced a pancreatic cancer diagnosis. They offer understanding, encouragement, and guidance.
Join our Facebook Support Group or consider joining one of our
Boards or Committees.
🧍‍♀️ Caregiver Health
Caring for a loved one with pancreatic cancer can be emotionally and physically demanding. Caregiver-focused programs and respite care can help prevent burnout. We recommend reaching out to Gilda’s Club for trusted caregiver support and resources.
🌿 Integrative Therapies
Incorporating practices such as meditation, yoga, gentle exercise, and nutrition support can improve overall well-being and quality of life during treatment.
💜 Connect with a Sky Advocate
Many of our Board Members, Committee Members, and volunteers are either survivors or have supported a loved one through a pancreatic cancer path.
We would be happy to connect you with someone who understands what you’re going through.

Contact Annie to be matched with a supportive Sky Advocate:
📧 Annie@SkyFoundationInc.org
📞 248-385-5143

Glossary & FAQ

Adenocarcinoma: Most common pancreatic cancer type.
Biopsy: Tissue sampling to confirm diagnosis.
CA 19-9: Tumor marker used for monitoring, not diagnosis.
EUS (Endoscopic Ultrasound): Imaging test for detailed pancreas evaluation.
Whipple Procedure: Complex surgery for tumors in the head of the pancreas.
Palliative Care: Specialized care to improve quality of life alongside treatment.

FAQ Highlights

  • How is staging determined? – Imaging, biopsy, and tumor spread.
  • Should I get genetic testing? – This can be an important conversation with your medical team. (Your care team can advise based on your situation.)
  • What if surgery isn’t possible? – Options include chemotherapy, radiation, targeted therapy, or clinical trials.
  • Where can I find clinical trials? – TriCanHealth.com (and ClinicalTrials.gov).

Closing Note

Pancreatic cancer care requires expert guidance, advanced treatments, and strong support systems. At Sky Foundation, we are here to connect patients and caregivers with top medical teams, clinical trial opportunities, and a supportive community that understands this journey.

read more

Post-Recovery Care & Recurrence Prevention in Pancreatic Cancer

Healthy lifestyle tips and caregiver support after treatment.

Completing treatment for pancreatic cancer—whether surgery, chemotherapy, or participation in clinical trials—is a major milestone. For survivors, caregivers, and families, the next stage brings new questions: How do we support recovery? What can we do to reduce the risk of recurrence? At Sky Foundation, our survivor-led leadership and committees provide insight from people who have walked this road, offering practical guidance and hope for the future.

Supporting Physical Recovery

Recovery looks different depending on the type of treatment. Caregivers can help by focusing on daily needs that support healing:

  • Nutrition: Work with a dietitian to build a nutrient-rich plan that supports digestion and weight stability.
  • Hydration: Encourage consistent fluid intake to reduce fatigue and aid digestion.
  • Activity: Support gentle movement, like walking or light stretching, to rebuild stamina.
  • Rest: Allow for frequent breaks, naps, and quiet spaces to avoid overexertion.

📖 Resource: American Cancer Society – Life After Cancer
📖 Resource: Oncology Nutrition – Recovery Diet Guidance

Emotional Healing After Treatment

Transitioning from active treatment to survivorship can bring unexpected emotions. Survivors may feel relief, but also anxiety about recurrence.

  • Normalize emotions: Understand that fear and worry are common post-treatment.
  • Seek counseling: Professional help can address post-treatment stress.
  • Join survivorship groups: Connecting with others who’ve completed treatment provides perspective and reassurance.

Sky Foundation offers survivor and caregiver communities where families can share experiences and support one another in this new chapter.

📖 Resource: Cancer Support Community – Life After Cancer

Preventing Recurrence: Healthy Lifestyle Tips

While no plan can fully prevent recurrence, adopting healthy habits may reduce risk and improve overall well-being.

  • Nutrition: Focus on whole foods, fruits, vegetables, lean proteins, and healthy fats. Limit processed foods and red meat.
  • Exercise: Aim for at least 150 minutes of moderate exercise per week, adjusted for recovery stage.
  • Weight management: Maintain a healthy weight to reduce strain on the body.
  • Quit smoking & limit alcohol: Both increase risk of recurrence and other health issues.
  • Routine screenings: Follow up with all imaging, blood tests, and medical visits.

📖 Resource: National Cancer Institute – Cancer Prevention Overview
📖 Resource: Mayo Clinic – Pancreatic Cancer Follow-Up Care

Role of Caregivers in Survivorship

Caregivers remain important after treatment ends. Roles often include:

  • Helping manage lingering side effects such as fatigue or digestive issues.
  • Encouraging healthy lifestyle changes.
  • Accompanying loved ones to follow-up appointments.
  • Providing reassurance when fear of recurrence surfaces.

Sky Foundation’s caregiver committees provide opportunities to learn strategies directly from other families who have supported loved ones in recovery.

Legacy of Care

Celebrating recovery is also a time to reflect on impact. Many survivors and families choose to give back by supporting others still on this journey. Sky Foundation’s Legacy Giving program allows families to create lasting impact by funding survivorship programs, caregiver resources, or research through their will or estate planning—ensuring recovery stories inspire hope for years to come.

Helpful Resources at a Glance

Key Takeaway

Recovery after pancreatic cancer treatment is a new chapter filled with both hope and uncertainty. By focusing on physical healing, emotional support, and healthy lifestyle choices, caregivers and survivors can strengthen resilience and reduce recurrence risk. Sky Foundation provides survivor-led communities, caregiver resources, and Legacy Giving opportunities to ensure that recovery journeys inspire lasting hope and progress.

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Recently Diagnosed with Pancreatic Cancer | Sky Foundation Guide

Being diagnosed with pancreatic cancer can feel overwhelming. This page is designed to provide accurate information, structured guidance, and trusted resources to help you understand your diagnosis and take your next steps with confidence.

Table of Contents

  1. Welcome & Understanding Your Diagnosis
  2. Next Steps After Diagnosis
  3. Treatment Options
  4. Clinical Trials Access
  5. Resources for Patients & Caregivers
  6. Glossary & FAQ 

Understanding Your Diagnosis

Pancreatic cancer begins in the pancreas, an organ that helps regulate blood sugar and produces enzymes for digestion. The most common type is pancreatic ductal adenocarcinoma (PDAC), which arises in the ducts of the pancreas. Less common types include neuroendocrine tumors.

Staging (localized, borderline resectable, locally advanced, or metastatic) is determined through imaging (CT, MRI, EUS) and biopsy.

📖 Resource: National Cancer Institute – Pancreatic Cancer

Next Steps After Diagnosis

Confirm Your Diagnosis and Stage – Use imaging, biopsy, and bloodwork (including CA 19-9) to confirm the diagnosis and determine the stage of pancreatic cancer.

Seek a Second Opinion – Outcomes often improve when care is coordinated through high-volume cancer centers. Sky Foundation partners closely with Henry Ford Health, Karmanos Cancer Institute, and the University of Michigan Rogel Cancer Center—and we can help connect you directly to any of these hospital systems upon request.

Get Genetic Testing – Genetic testing is now standard for all pancreatic cancer patients. It not only helps guide treatment, but also gives your family valuable insight into their own potential risks. If you have a first-degree relative with pancreatic cancer, we strongly encourage scheduling genetic testing to protect yourself and your loved ones. Find a genetic councselor near you on our Genetic Counselors Page.

Understand Your Treatment Pathways – Common treatment options include surgery, chemotherapy, radiation, clinical trials, and palliative care. Understanding each pathway helps you and your care team make informed decisions tailored to your needs.

Explore Clinical Trials Early – Access to new and emerging therapies can improve survival and quality of life. We recommend TriCan Health, which can match your specific case details to active clinical trials that may be the best fit for you.

Build a Multidisciplinary Care Team – Assemble a team that includes experienced surgeons, oncologists, gastroenterologists, and nutritionists. If you’re a candidate for the Whipple procedure, research your surgeon carefully—experience matters. Look for someone who has performed hundreds, ideally thousands of successful Whipple surgeries. Don’t hesitate to ask questions and gather all the information you need to make a confident decision.

Prepare for Appointments – Bring a trusted caregiver and a written list of questions to each visit. Staying organized ensures you get the answers and support you need at every step. Refer to our questions for yourself and your medical team page. 

Treatment Options

  • Surgery: Whipple procedure, distal pancreatectomy, or total pancreatectomy (curative intent).
  • Chemotherapy: FOLFIRINOX, gemcitabine + nab-paclitaxel, or gemcitabine alone.
  • Radiation Therapy: For borderline resectable or locally advanced disease, or symptom relief.
  • Targeted Therapy & Immunotherapy: PARP inhibitors for BRCA1/2 mutations; pembrolizumab for MSI-H tumors.
  • Clinical Trials
  • Palliative Care: Pain management, nutrition counseling, enzyme replacement, and emotional support.

Clinical Trials Access

Clinical trials test new therapies, including targeted drugs and immunotherapies. Patients often benefit from enrolling early. Clinical Trials are often looked at when patients “have no other options”.  But in the words of pancreatic cancer survivor, Kay Kays “Clinical Trials should be the Appetizer, not the dessert.” meaning these should not be a last resort, and rather a valuable resource at the beginning of your path.  

Click here to discover what works best for you on TriCan Health.

Resources for Patients & Caregivers

Support & Emotional Well-Being

Counseling & Mental Health
Emotional health is an important part of your care. Oncology social workers, psychologists, and cancer support groups can help manage anxiety, depression, and the emotional challenges that come with a diagnosis.

Peer Support Communities
At Sky Foundation, our community includes many individuals who have personally experienced a pancreatic cancer diagnosis. They offer understanding, encouragement, and valuable guidance.
Join our Facebook Support Group to connect with others, or consider getting more involved by joining one of our Boards or Committees to further support our mission.

Caregiver Health
Caring for a loved one with pancreatic cancer can be emotionally and physically demanding. Caregiver-focused programs and respite care can help prevent burnout. We recommend reaching out to Gilda’s Club for trusted caregiver support and resources.

Integrative Therapies
Incorporating practices such as meditation, yoga, gentle exercise, and nutrition support can improve overall well-being and quality of life during treatment.

Connect with a Sky Advocate
Many of our Board Members, Committee Members, and volunteers are either survivors or have supported a loved one through a pancreatic cancer path. We would be happy to connect you with someone who understands what you’re going through and can offer personal insight and encouragement.
Contact Annie, Sky’s Executive Director, to be matched with a supportive Sky Advocate:
📧 Annie@SkyFoundationInc.org
📞 248-385-5143

Glossary & FAQ

Adenocarcinoma: Most common pancreatic cancer type.
Biopsy: Tissue sampling to confirm diagnosis.
CA 19-9: Tumor marker used for monitoring, not diagnosis.
EUS (Endoscopic Ultrasound): Imaging test for detailed pancreas evaluation.
Whipple Procedure: Complex surgery for tumors in the head of the pancreas.
Palliative Care: Specialized care to improve quality of life alongside treatment.

FAQ Highlights:

  • How is staging determined? – Imaging, biopsy, and tumor spread.
  • Should I get genetic testing? – Yes, recommended for all patients.
  • What if surgery isn’t possible? – Options include chemotherapy, radiation, targeted therapy, or clinical trials.
  • Where can I find clinical trials? – TriCanHealth.com

Closing Note

Pancreatic cancer care requires expert guidance, advanced treatments, and strong support systems. At Sky Foundation, we are here to connect patients and caregivers with top medical teams, clinical trial opportunities, and a supportive community that understands this journey.

read more

Pancreatic Cancer Treatment Options | Surgery, Chemo & Care

Treatment for pancreatic cancer depends on the type, stage, and overall health of the patient. Care is typically provided by a multidisciplinary team that includes surgeons, oncologists, gastroenterologists, and palliative care specialists.

1. Surgery

Surgery is the only treatment with the potential to cure pancreatic cancer. However, only about 15–20% of patients are candidates because the cancer is often diagnosed at an advanced stage.

Common surgical procedures:

  • Whipple procedure (pancreaticoduodenectomy): Removes the head of the pancreas along with part of the stomach, duodenum, bile duct, and gallbladder. This is the most common surgery for tumors in the head of the pancreas.
  • Distal pancreatectomy: Removes the body and tail of the pancreas, often with the spleen.
  • Total pancreatectomy: Removes the entire pancreas, bile duct, gallbladder, and part of the stomach and small intestine. Patients will require lifelong insulin and enzyme replacement.

📖 Resource: Johns Hopkins Medicine – Surgery for Pancreatic Cancer

2. Chemotherapy (Systemic Therapy)

Chemotherapy uses drugs that circulate throughout the body to kill cancer cells. It can be given:

  • Neoadjuvant (before surgery): To shrink tumors and increase surgical success.
  • Adjuvant (after surgery): To reduce the risk of recurrence.
  • Primary treatment: For patients with locally advanced or metastatic disease.

Standard regimens include:

  • FOLFIRINOX (combination of fluorouracil, leucovorin, irinotecan, oxaliplatin) – typically for patients in good health who can tolerate intensive therapy.
  • Gemcitabine + nab-paclitaxel – often used when FOLFIRINOX is not appropriate.
  • Gemcitabine alone – an option for patients who cannot tolerate combination therapy.

📖 Resource: American Cancer Society – Chemotherapy for Pancreatic Cancer

3. Radiation Therapy

Radiation uses high-energy X-rays to kill cancer cells. It may be used in combination with chemotherapy (chemoradiation) or alone.

When radiation is used:

  • To shrink borderline resectable tumors before surgery.
  • To control locally advanced cancer when surgery is not possible.
  • To relieve symptoms such as pain or bleeding.

📖 Resource: National Cancer Institute – Pancreatic Cancer Treatment

4. Targeted Therapy and Immunotherapy

Advances in genetics and molecular profiling have led to new treatment options for selected patients.

  • PARP inhibitors (e.g., olaparib): For patients with inherited BRCA1/2 or PALB2 mutations.
  • MSI-H or dMMR tumors: May respond to immunotherapy drugs such as pembrolizumab (a PD-1 inhibitor).
  • TRK fusion-positive tumors: May respond to TRK inhibitors such as larotrectinib.

Testing tumors for genetic changes (biomarker testing) is critical to determine eligibility.

📖 Resource: FDA – Targeted Therapies for Pancreatic Cancer

5. Palliative and Supportive Care

Palliative care is not only for end-of-life care. It should begin at diagnosis to improve quality of life.

  • Pain management: Often involves medications, nerve blocks, or celiac plexus neurolysis.
  • Digestive support: Pancreatic enzyme replacement therapy (PERT) helps manage malabsorption.
  • Nutritional counseling: Maintains weight and strength during treatment.
  • Psychological and social support: Reduces anxiety and caregiver stress.

📖 Resource: Cancer.Net – Palliative Care for Pancreatic Cancer

Key Takeaway

Treatment may involve surgery, systemic therapy, radiation, or a combination of approaches. Genetic and biomarker testing are increasingly important for guiding therapy, and palliative care should be integrated from the start.

 

NEXT ARTICLE: Clinical Trials Access & Information

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2024 Cancer Statistics: Pancreatic Cancer Survival Rate Increases to 13%

Pancreatic Cancer 5 year survival rate increases to 13% which means more hope. In terms of lives extended, this one percentage point increase is significant. It means 664 more loved ones will enjoy life’s moments five years after their pancreatic cancer diagnosis. The research in early detection is translating to improved survival rates.

American Cancer Society releases 2024 statistics. There is some good news, but some alarming statistics. The good news is research is helping prevent and diagnosis cancer. 4.1 millions fewer people will pass away from cancer in 2024. However, the cases will climb to startling levels. External factors such as lifestyle and social disparities are contributing factors.

Although U.S. cancer cases will eclipse 2 million for the first time this year, there is good news. Lower smoking rates, earlier detection and improved treatments have lowered death rates over the past three decades, a new report said.

The American Cancer Society’s annual cancer statistics report projects 611,720 cancer deaths this year, a slight increase from a year ago. The cancer death rate dropped 33% from 1991 through 2021, according to the most recent statistics available, the group said, due to cutting edge research and vaccination treatments.

But researchers are concerned about increasing rates of cancer in younger populations and the types of of cancer, including the pancreas. Click here to read more.

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Five-Year Pancreatic Cancer Survival Rate Increases to 12%

We are excited to announce the new statistic for the 5-year survival rate of pancreatic cancer is now 12%!  PanCAN featured a great article on this increased rate, but explained how there is still so much work that needs to be done. 

This is the first time since 2017 that the survival rate has gone up two years in a row, a promising upward trend that points to continued progress in the fight against this tough disease. It also represents lives saved: A one percentage point increase means 641 more loved ones who will enjoy life’s moments five years after their pancreatic cancer diagnosis.

Still, there’s more work to be done, as the Facts & Figures report also reveals that an estimated 64,050 Americans will be diagnosed with pancreatic cancer in 2023, more people than ever before. Approximately 50,550 Americans are expected to die from the disease this year.

And while pancreatic cancer is currently the 10th most commonly diagnosed cancer in the U.S., it remains the third-leading cause of cancer-related deaths. Pancreatic cancer is on track to become the second leading cause of cancer-related deaths before 2030.

Sky Foundation’s research has continued to play an integral role in advancing this statistic.   We are grateful to our generous donors and supporters who have assisted us in funding researchers across the nation to address this issue.  

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Alex Trebek Loses his Battle Against Pancreatic Cancer on November 8, 2020

Alex Trebek Loses his Battle Against Pancreatic Cancer on November 8, 2020

Sky Foundation was deeply saddened by the passing of Alex Trebek. By openly sharing his diagnosis and treatment of pancreatic cancer he brought awareness to millions of people.
Pancreatic cancer is now the third-deadliest cancer and we can only affect the trajectory of this terrible disease through education, awareness, and research.
In the category of most-loved game show hosts the world will answer, “Who is Alex Trebek?” He will be missed by all those who adored him and watched him every evening on “Jeopardy!” Rest in peace, Alex.

Alex Trebek of ‘Jeopardy!’ dies at 80 after pancreatic cancer battle

Bill Keveney

USA TODAY

Game show legend Alex Trebek, the beloved “Jeopardy!” host who showed dignity and perseverance in dealing with a Stage 4 pancreatic cancer diagnosis in March 2019, died Sunday. He was 80.

” ‘Jeopardy!’ is saddened to share that Alex Trebek passed away peacefully at home early this morning, surrounded by family and friends. Thank you, Alex,” according to a statement from “Jeopardy!”

Trebek was synonymous with longtime top-rated “Jeopardy!,” the brainiest of TV quiz shows, which he hosted since its syndicated revival premiered in 1984 (Art Fleming hosted an earlier NBC version from 1964 to 1975.). Will Ferrell’s “Saturday Night Live” impersonation both underlined and burnished Trebek’s exalted cultural status.

The Sudbury, Ontario-born host, who gained U.S. citizenship in 1998, enjoyed a substantial game show career before taking on “Jeopardy!,” hosting shows such as “The Wizard of Odds,” “Double Dare,” “High Rollers,” “Battlestars,” “Classic Concentration” and “To Tell the Truth.”

Read the full article at: https://www.usatoday.com/…/jeopardy-host…/1885204001/

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Eighteen Important Words to Know if You Have Pancreatic Cancer

Let’s Win talks about the “18 words’ you need to be aware of when being diagnosed with pancreatic cancer.
When you or someone you love receives a pancreatic cancer diagnosis, it can feel a bit like you’ve arrived in a foreign land.

The decisions you make are potentially life-changing and people all around you are speaking in terms you don’t understand. “It’s natural for patients and loved ones to begin reading everything they can about pancreatic cancer, and that’s a good practice,” Dr. Allyson Ocean, medical oncologist at NewYork-Presbyterian Hospital/Weill Cornell Medical Center in New York. “But often when they begin reading medical journals or talking to members of their health care team, they get lost fixating on terms they don’t know.”

One way to get a leg up on your new world? Learn the language. Here are 18 words you are likely to encounter, and where you might hear them.

Diagnostics

When you have cancer of any type, receiving the correct diagnosis is paramount. Unfortunately, the signs and symptoms of pancreatic cancer can be vague and can mimic other conditions. While most doctors start with a simple computed tomography scan (CT), the following tests are also often used for diagnosing pancreatic cancer. With these tests doctors can better see a tumor’s size and location, as well as obtain a biopsy.

1. Endoscopic retrograde cholangiopancreatography (ERCP): ERCP combines X-ray technology with an endoscope—a thin, flexible, illuminated tube—to spot problems in the liver, pancreas, and bile ducts. Doctors place the tube down your throat and through the esophagus, stomach, and the duodenum (the first part of the small intestine). Then they pass a dye through a small tube into the scope to highlight the lower organs on X-ray.

2. Endoscopic ultrasound (EUS): Like ERCP, EUS involves inserting an endoscope into the mouth and through the esophagus, stomach, and the duodenum. A small ultrasound probe at the tip of the tube emits high-frequency sound waves to capture detailed images of the chest, digestive tract, pancreas, bile ducts, and liver.

Treatment

When it comes to cancer treatment, you probably already know about radiation and chemotherapy. The following terms are also important for understanding pancreatic cancer treatment protocols.

3. Neoadjuvant therapy: The term “neoadjuvant” is used to describe treatment such as chemotherapy or radiation that is given before surgery.

4. Adjuvant therapy: Adjuvant therapy is treatment given after surgery.

5. Resectable pancreatic cancer: A cancer that is resectable means that the tumor lies within the pancreas or extends slightly beyond it. It’s resectable because it is free and clear of critical structures such as arteries and veins.

6. Borderline resectable pancreatic cancer: Tumors are given this classification if they are confined to the pancreas, but approach nearby structures. Doctors may not be able to remove the entire cancer without causing severe or debilitating symptoms.

7. Immunotherapy: Unlike chemotherapy and radiation, this unique form of cancer treatment harnesses the power of the immune system to fight cancer. There are different types of immunotherapy, including vaccines, monoclonal antibodies, and checkpoint inhibitors.

8. Stent: A stent is a small metal or plastic tube that doctors use to open a blocked duct. Doctors might place a stent in your pancreatic duct or your bile duct to help treat jaundice, or they might place one in the duodenum to treat sickness and restore your appetite.

9. Pancreatectomy: A surgical procedure where doctors remove all or part of the pancreas.

10. Whipple procedure: The Whipple procedure is an intense surgical procedure that involves removing part of the stomach, the duodenum, head of the pancreas, part of the bile duct, gallbladder, and lymph nodes in the area of the pancreas.

To continue reading the next 8, visit Let’s Win’s website Here.

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12-year Survivor Funds Research and Gives Hope

PanCAN wrote a phenomenal article on our founder, Sheila Sky Kasselman.  You can visit PanCAN’s website for more information and read the entire article below:

Sheila Sky Kasselman has experienced more than a decade’s worth of challenges, but the 12-year pancreatic cancer survivor doesn’t let that get her down.

“Every day is a new beginning,” Kasselman said. “I’m here and functional. That’s the best news.”

In 2007, Kasselman was diagnosed with stage I pancreatic cancer. Though her disease was caught at an early stage, she had been suffering for nine months before doctors found the cause.

“People don’t realize how depressed you get when you don’t know what is going on,” Kasselman shared.

“And depression is a symptom of pancreatic cancer. In fact, I had many more symptoms.”

They included nausea, weight loss, diabetes, back pain and jaundice.

When the symptoms started, her tumor was small and hidden under an artery, so the doctors couldn’t see it on a CT scan. When it grew large enough to collapse her bile duct, jaundice set in, triggering another scan.

This time, they could see the tumor.

Luckily, she was still eligible for surgery.

For eligible patients, surgery is the best option for long-term survival of pancreatic cancer.

Kasselman had chemotherapy and radiation therapy, followed by the Whipple procedure.

As a result of the treatment, she now has type 3c diabetes. This type of diabetes is caused by pancreatic diseases, like pancreatic cancer or pancreatitis, or removal of some or all of the pancreas through surgery.

Between the removal of organs during the surgery and the diabetes that followed – along with further complications due to kidney stones – Kasselman continues to have huge nutritional challenges.

Even now, more than a decade later, she remains on an extremely limited diet. She drinks a ton of water to stay hydrated and takes pancreatic enzymes with every meal, as well as vitamin D.

But Kasselman is still a force to be reckoned with.

Weighing in at only 95 pounds, she’s strong – exercising, doing Pilates and walking on a regular basis.

She has also kept her sense of humor and is committed to helping others learn about this disease.

“It is equally important for me to raise awareness and to raise funds for research.

“So many people don’t get to the doctor in time. Late diagnosis breaks my heart.”

Just four months after her Whipple surgery, Kasselman started Sky Foundation to raise awareness and fund research for the early detection and treatment of pancreatic cancer.

Sky Foundation is a member of the World Pancreatic Cancer Coalition, a global alliance in the fight against the disease.

The foundation has also funded Pancreatic Cancer Action Network (PanCAN) initiatives.

“I think PanCAN is doing excellent work,” Kasselman said. “I have the utmost respect for everything that PanCAN does.”

She is particularly excited about the new dedicated federal pancreatic cancer research program – and credits PanCAN’s advocacy efforts for that legislation. She also supports PanCAN’s research into the connection between diabetes and pancreatic cancer.

Much of her life focuses on pancreatic cancer – except when she’s playing competitive bridge. “It’s the only way I can get away from the disease and turn my brain off!” Kasselman said.

“My devotion to this disease remains as intense as it was when I started the foundation.”

Kasselman is often contacted by others who have been recently diagnosed with the disease, and she always listens and provides support.

Most importantly, she is a beacon of hope.

Kasselman doesn’t focus on the struggles. She celebrates what she has accomplished since her diagnosis and her commitment to Sky Foundation. She also celebrates getting to see her four grandchildren grow up!

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Searching For A Cure

Sheila Sky Kasselman was a doting grandmother enjoying life when she started to feel depressed.

“I also lost a ton of weight. I was nauseous all the time. I became diabetic. And then I wasn’t diabetic. So, I had a lot of symptoms and then I jaundiced,” explained Kasselman.

In September of 2007, doctors explained why – pancreatic cancer.

“When I was diagnosed not all that long ago, there was no one talking about this disease. It was a silent cancer. And I decided that if I lived, I was going to shout. And I’m still shouting.”

Kasselman is “shouting” through her non-profit she created months after her successful whipple surgery back in 2008.

The Sky Foundation aims to raise awareness about the disease and funding for innovative research.

Check out the VIDEO segment and full article HERE.

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What We Do

 At Sky Foundation, Inc., we raise awareness and fund innovative research for the early detection and treatment of pancreatic cancer.
Through community events, social media, and unique awareness initiatives, we educate the public, connect families with resources, and raise critical funds for research.

We also emphasize the importance of genetic counseling for individuals with a family history of pancreatic cancer—empowering people to take preventive action and detect the disease early.

Research

Our mission begins with research. Each year, Sky Foundation awards seed grants to doctors and scientists pursuing promising pancreatic cancer studies and medical treatment breakthroughs.

  • Each seed grant provides $50,000 in initial funding to help researchers advance early-stage projects.

  • Our Scientific Advisory Committee (SAC), composed of leading experts in pancreatic cancer, carefully reviews and recommends which proposals to fund.

  • Researchers provide annual progress updates to ensure accountability and to evaluate potential for continued or expanded funding.

Sky Foundation’s grants help fill critical funding gaps—enabling innovative ideas to grow into competitive projects that can later secure major support from the National Institutes of Health (NIH) and other national institutions.

We proudly fund researchers across Michigan and throughout the United States, expanding our impact coast to coast.

👉 Meet Our Researchers

Awareness

Awareness and education are at the heart of everything we do.
Because pancreatic cancer is often detected late, recognizing even subtle body changes and understanding your family history can make all the difference.

Our awareness efforts include:

  • Public events that bring communities together for education and action

  • Campaigns during Pancreatic Cancer Awareness Month (November) and throughout the year

  • Partnerships with hospitals, corporations, and community organizations to share life-saving information

By spreading awareness, we aim to give people the knowledge and confidence to advocate for themselves and their loved ones.

Genetic Counseling

Genetic counseling is an important step toward prevention and early detection.
We recommend genetic counseling for anyone with:

  • A first-degree relative (parent, sibling, or child) diagnosed with pancreatic cancer

  • Two or more second-degree relatives (grandparents, aunts, uncles, or cousins) with a history of the disease

🔗 Find a Genetic Counselor in Michigan

Sky Support Circle

At Sky Foundation, we know that community is one of the most powerful forms of healing.
Our Sky Support Circle is made up of dedicated Sky Advocates—individuals who have walked a similar path, either as survivors or as advocates for loved ones affected by pancreatic cancer.

These volunteers provide:

  • Emotional support and understanding during difficult times

  • Guidance drawn from their own lived experience

  • Connection to resources, hope, and community

Whether you’re newly diagnosed, caring for a loved one, or seeking understanding after loss, our Sky Advocates are here to listen and share insight that only someone who’s been there can provide.

If you’d like to be connected with a Sky Advocate, reach out to:
📧 Annie Dalton, Executive Director – Annie@SkyFoundationInc.org
📞 248-385-5143

Outreach

Our outreach efforts extend beyond research and awareness—we believe in building community and sparking conversations that matter.

  • We host special events that unite patients, caregivers, and supporters.

  • We collaborate with media partners, civic groups, and local organizations to share resources and encourage early detection.

  • We produce educational videos, often using relatable humor to open dialogue about a difficult subject.

Visit our YouTube Channel to watch Sky Foundation videos that educate, inspire, and bring hope to those impacted by pancreatic cancer.

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