Sita Kugel, PhD Fred Hutch Cancer Center

Sita Kugel, Ph.D., is an Associate Professor in the Human Biology Division and serves as the Director of Basic and Translational Research in GI Oncology and the Co-director of the Pancreatic Cancer program. The central theme of her research group is to study how the dysregulation of chromatin modifying enzymes contribute to hepatopancreatic biliary cancers and, further, whether these pathways present liabilities that can be exploited for cancer therapy. She is particularly interested in exploring the biology of different transcriptional and genetic subtypes of pancreatic cancer and cholangiocarcinoma. How the epigenome influences subtype determination and discovering unifying biological characteristics that define these subtypes, which with deeper understanding could improve patient therapy.