Balance of Two Enzymes Linked to Pancreatic Cancer Survival
Researchers are finding new leads to an earlier detection of pancreatic cancer diagnoses.
Protein Kinase C (PKC) enzymes are crucial for a number of cellular activities, including cell survival, proliferation and migration — functions that must be carefully controlled lest cells get out of control and form a tumor. Researchers at University of California San Diego School of Medicine found that another enzyme, called PHLPP1, acts as a “proofreader” to keep careful tabs on PKC. In pancreatic cancer, they discovered that high PHLPP1 levels lead to low PKC levels, which is associated with poor patient survival.
Read the whole article on UC San Diego Health HERE.