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SKY Updates

Johns Hopkins Study Identifies “Master Gene” Driving Pancreatic Cancer Spread

A groundbreaking study from researchers at Johns Hopkins has identified a key “master gene” that plays a powerful role in driving pancreatic cancer metastasis—the process by which cancer spreads to other organs. The research highlights how this gene activates pathways that allow pancreatic tumors to become more aggressive and invasive.

Metastasis is responsible for the majority of pancreatic cancer–related deaths, making discoveries like this especially significant. By understanding the genetic mechanisms that enable cancer cells to spread, scientists can begin developing targeted therapies aimed at slowing or stopping that progression.

Findings like these reinforce why continued investment in pancreatic cancer research is so critical. Each new discovery brings us closer to more effective treatments—and ultimately, better outcomes for patients and families impacted by this disease.

Read the full article on SciTech Daily here.

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Sky Support Circle

Continuing the Legacy of Compassion The Sky Support Circle was created in the spirit of our founder, Sheila Sky Kasselman, who built Sky Foundation on one simple but powerful belief — that no one facing
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2025 Sky Awarded Researchers

Dr. Harrison L. Hiraki Harrison L. Hiraki, PhD — Rogel and Blondy Cancer Center (University of Michigan) Dr. Hiraki is advancing our understanding
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Episode #102: Whipple Diabetics

Dr. Kathleen Estrada discusses the functions of the pancreas, focusing on its endocrine role in glucose regulation. The pancreas contains islets of Langerhans, which secrete insulin, glucagon, and somatostatin. Insulin lowers blood sugar levels, while
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